Heparin-induced thrombocytopenia physical examination

Heparin-induced thrombocytopenia
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Shyam Patel [2]

Physical Examination

Skin Exam

• Skin necrosis from thrombotic physiology
• Petechiae from thrombocytopenia
• Purpura from thrombocytopenia
• Ecchymoses from thrombocytopenia

Cardiopulmonary Exam

• Tachypnea from pulmonary embolism
• Tachycardia from pulmonary embolism
• Hypoxia from pulmonary embolism

Musculoskeletal Exam

• Leg swelling from deep vein thrombosis
• Calf tenderness from deep vein thrombosis

Other Exam Findings

• Mucosal bleeding from thrombocytopenia (i.e. oral, nasal, urinary, menstrual, gastrointestinal, or other)
• Abdominal tenderness from mesenteric venous thrombosis
• Neurologic deficits from cerebral arterial or dural venous sinus thrombosis