Hashimoto's thyroiditis overview
|
Hashimoto's thyroiditis Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Hashimoto's thyroiditis overview On the Web |
|
American Roentgen Ray Society Images of Hashimoto's thyroiditis overview |
|
Risk calculators and risk factors for Hashimoto's thyroiditis overview |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]
Overview
Hashimoto's thyroiditis or chronic lymphocytic thyroiditis is an autoimmune disease where the body's own antibodies attack the cells of the thyroid.
Historical Perspective
Hashimoto's thyroiditis was first described by Hashimoto Hakaru in 1912. He named it struma lymphomatosa which was renamed as Hashimoto's thyroiditis in 1931.
Classification
Pathophysiology
Hashimoto's thyroiditis (HT) is characterized by Lymphocytic infiltration of the thyroid gland and production of antibodies that recognize thyroid-specific antigens.The pathogenesis is not yet completely understood. It is currently thought that the disease is caused by abnormalities in cellular and humoral immunity which results in a localized cell-mediated immune response directed toward the thyroid parenchymal cells. This results in the decreased production of thyroid hormones.