Addison's disease differential diagnosis

Addison's disease Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Addison's disease from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
X Ray
CT
MRI
Ultrasound
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Addison's disease differential diagnosis On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Addison's disease differential diagnosis All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Addison's disease differential diagnosis
CDC on Addison's disease differential diagnosis
Addison's disease differential diagnosis in the news
Blogs on Addison's disease differential diagnosis
Directions to Hospitals Treating Addison's disease
Risk calculators and risk factors for Addison's disease differential diagnosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Differentiating Addison's disease from other Diseases

Addison's disease should be differentiated from the following diseases:

• Acanthosis nigricans
• Anorexia nervosa
• Chronic fatigue syndrome
• Depression
• Disorders of oral pigmentation
• Hyperthyroidism
• Laugier-Hunziker Syndrome
• Lentigo
• Malignant melanoma
• Melasma
• Occult malignancy
• Oral manifestations of systemic diseases
• Peutz-Jeghers syndrome
• Type 1 diabetes mellitus
• Vitiligo

	Harmone or pathway defective
ACTH deficiency	↓ ACTH	Pituitary gland
Congenital adrenal hyperplasia (CAH)	↓ Corticosteroid hormones	Adrenal gland
Adrenoleukodystrophy	ABCD1 gene on the X chromosome	White matter of the nervous system and the adrenal cortex
Autoimmune polyendocrine syndrome type II ( Schmidt syndrome)	↓Parathyroid harmone ↓Insulin ↓Sex harmones	parathyroid gland Pancreas Gonads
Autoimmune polyendocrine syndrome type I, (APS type 1) ( APECED syndrome)	Autoimmune Polyendocrinopathy (APE), Candidiasis (C) and Ectodermal Dysplasia (ED)	Autoimmune Polyendocrinopathy (APE) Candidiasis (C) Ectodermal Dysplasia (ED)
Hemachromatosis
Hyperthyroidism