Psittacosis medical therapy
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Risk calculators and risk factors for Psittacosis medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Psittacosis is treated with tetracyclines. Remission of symptoms usually is evident within 48-72 hours. However, relapse can occur, and treatment must continue for at least 10-14 days after fever abates. Since tetracyclines are contraindicated during pregnancy and infancy the preferred treatment is azithromycin.
Medical Therapy
Antimicrobial Regimen
- 1. Psittacosis [1]
- 1.1 Adult
- Preferred regimen (1): Doxycycline 100 mg PO bid for 10-21 days
- Preferred regimen (2): Tetracycline 500 mg PO qid for 10-21 days
- Alternative regimen: Minocycline
- 1.2 Pediatric
- 1.2.1 Mild infection, Infants >3 months
- Preferred regimen: Azithromycin 10 mg/kg PO qd on day 1 THEN 5 mg/kg PO q24h for 4 days; (Maximum, 500 mg for 1st dose, 250 mg for subsequent doses)
- 1.2.2 Moderate-severe infection, Infants >3 months
- Preferred regimen: Azithromycin 10 mg/kg IV q24h for 2 days THEN 5 mg/kg PO qd for 3 days; (Maximum, 500 mg/dose IV; 250 mg/dose PO)
- 1.3 Pregnant Patients
- Preferred regimen: Azithromycin 500 mg PO on day 1 THEN by 250 mg qd on days 2-5 OR 500 mg IV as a single dose for at least 2 days, followed by 500 mg PO qd for 7- 10 days
References
- ↑ Bennett, John (2015). Mandell, Douglas, and Bennett's principles and practice of infectious diseases. Philadelphia, PA: Elsevier/Saunders. ISBN 978-1455748013.