De Quervain's thyroiditis medical therapy
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De Quervain's thyroiditis Microchapters |
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Differentiating De Quervain's thyroiditis from other Diseases |
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Diagnosis |
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Treatment |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Furqan M M. M.B.B.S[2]
Overview
The mainstay of therapy for de Quervain's thyroiditis is aspirin or non-steroidal anti-inflammatory drugs for pain control. Beta-adrenergic blockers are recommended for the patients who develop thyrotoxic symptoms.
Medical Therapy
The drugs used in the treatment of De Quervain's thyroiditis are:[1][2]
- Asprin or NSAIDs
- Aspirin and non-steroidal anti-inflammatory drugs are used for pain control.
- Beta adrenergic blockers
- Beta-adrenergic blockers such as propranolol and atenolol are used for controlling thyrotoxic symptoms.
- Corticosteroids
- Corticosteroids usually show a dramatic response in severely ill patients within 24-48 hours.
- Levothyroxine:
- It is required if the patient develops hypothyroidism following the resolution of the hyperthyroid state.
Drug Regimen:
- Naproxen 500 to 1000 mg per day in two divided doses
- Ibuprofen 1200 to 3200 mg per day in three or four divided doses
- Prednisone 40 mg per day orally.
- Synthetic levothyroxine (L-T4) 1.6–1.8 μg/kg of body weight per day orally.
References
- ↑ Engkakul P, Mahachoklertwattana P, Poomthavorn P (2011). "Eponym : de Quervain thyroiditis". Eur. J. Pediatr. 170 (4): 427–31. doi:10.1007/s00431-010-1306-4. PMID 20886353.
- ↑ Yamamoto M, Saito S, Sakurada T, Fukazawa H, Yoshida K, Kaise K, Kaise N, Nomura T, Itagaki Y, Yonemitsu K (1987). "Effect of prednisolone and salicylate on serum thyroglobulin level in patients with subacute thyroiditis". Clin. Endocrinol. (Oxf). 27 (3): 339–44. PMID 3427792.