11β-hydroxylase deficiency epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mehrian Jafarizade, M.D [2]

Overview

Worldwide, the prevalence of 11β-hydroxylase deficiency is 1 per 100,000 persons. 11β-hydroxylase deficiency accounts for 5 percent of all cases of congenital adrenal hyperplasia and it is considered the second most frequent variant after 21-hydroxylase deficiency. It is estimated that 11-beta-hydroxylase deficiency occurs in 1 in 100,000 to 200,000 newborns. The incidence of 11β-hydroxylase deficiency is 1 per 100,000 persons. Also this disease is more common in Moroccan Jews living in Israel, occurring in approximately 20 in 100,000 newborns. 11β-hydroxylase deficiency affects males and females equally.

Epidemiology and Demographics

Prevalence

• Worldwide, the prevalence of 11β-hydroxylase deficiency is 1 per 100,000 persons.

Incidence

• 11β-hydroxylase deficiency accounts for 5 percent of all cases of congenital adrenal hyperplasia and it is considered the second most frequent variant after 21-hydroxylase deficiency. It is estimated that 11-beta-hydroxylase deficiency occurs in 1 in 100,000 to 200,000 newborns.
• Worldwide, the incidence of (insert disease state here) is 1 per 100,000 persons.
• 11β-hydroxylase deficiency is more common in Moroccan Jews living in Israel, occurring in approximately 20 in 100,000 newborns.

Gender

• 11β-hydroxylase deficiency affects males and females equally.

Race

• 11β-hydroxylase deficiency usually affects individuals of the Jewish race.