De Quervain's thyroiditis other diagnostic studies
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De Quervain's thyroiditis Microchapters |
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Differentiating De Quervain's thyroiditis from other Diseases |
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Diagnosis |
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Treatment |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]
Overview
The histological analysis in de Quervain's thyroiditis may show inflammatory cell infiltration and hurthle cells. Fine needle aspiration cytology helps to differentiate between the benign and malignant nodules.[1]
Other Diagnostic Studies
Fine needle aspiration cytology
Fine needle aspiration is usually done under ultrasound guidance and the sample is sent for cytology. It helps to differentiate benign thyroid nodules from the malignant lesions.
Gross Pathology
- The gland is usually diffusely enlarged, firm, and slightly lobular. The capsule is intact, and the cut surface is light-tan and has a slight lobular pattern.
- At autopsy, significant subarachnoid hemorrhage from the ruptured berry aneurysm was documented. In addition, the thyroid gland was mildly enlarged and firm. On cut section, the tissue was slightly pale.
Microscopic Pathology
Microscopically there is massive infiltration of the thyroid gland by lymphocytes and plasma cells. Germinal centers can often be seen in the gland. Thyroid follicles are usually absent and the few remaining follicles are devoid of colloid.