Euthyroid sick syndrome classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Classification

Euthyroid sick syndrome may be classified according to the level of thyroid hormones and the severity of the underlying disease into:

• Mild
• Moderate
• Severe
• Recovery

Euthyroid sick syndrome	T3 (80-180 ng/dl)	T4 (4.6-12 ug/dl)	FT4 (0.7-1.9 ng/dl)	TSH (0.4 to 4.0mIU/L)	Reverse T3 (90 to 350pg/mL)
Mild euthyroid sick syndrome	↓	N	N	N	↑
Moderate euthyroid sick syndrome	↓	N	N/↑	N/↑	↑
Severe euthyroid sick syndrome	↓	↓	N/↓	↓	↑
Recovery	N/↓	N	N	N	N/↑