Sheehan's syndrome laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

• An elevated/reduced concentration of serum/blood/urinary/CSF/other [lab test] is diagnostic of [disease name].
• Laboratory findings consistent with the diagnosis of [disease name] include [abnormal test 1], [abnormal test 2], and [abnormal test 3].
• [Test] is usually normal among patients with [disease name].
• Some patients with [disease name] may have elevated/reduced concentration of [test], which is usually suggestive of [progression/complication].

OR

• There are no diagnostic laboratory findings associated with [disease name].

Laboratory Findings

• Laboratory findings consistent with the diagnosis of Sheehan syndrome include:
  • Hyponatremia
  • Hypokalemia
  • Hypocalcemia
  • Hypomagnesemia
  • Hypophosphatemia
  • Decreased levels of anterior pituitary hormones in blood.
• Most sensitive test is inadequate prolactin and gonadotropin responses to stimulation.
• Baseline and stimulated anterior pituitary hormone level measurements.