Pheochromocytoma other diagnostic studies
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2] Mohammed Abdelwahed M.D[3]
Overview
Clonidine suppression test may be used in the diagnosis of pheochromocytoma.
Other Diagnostic Studies
- Clonidine suppression test may be used to diagnose pheochromocytoma.[1]
- Clonidine is a centrally-acting alpha-2 agonist used to treat high blood pressure.
- Clonidine mimics catecholamines in the brain and reduces the activity of the sympathetic nerves controlling the adrenal medulla.
- Healthy adrenal medulla will respond to the clonidine suppression test by reducing catecholamine production.
- Lack of a response (no reduction in catecholamine levels after test) is evidence of pheochromocytoma.
References
- ↑ Goupil R, Fountoulakis S, Gordon RD, Stowasser M (2015). "Urinary clonidine suppression testing for the diagnosis of pheochromocytoma". J Hypertens. 33 (11): 2286–93. doi:10.1097/HJH.0000000000000705. PMID 26335433.