Sheehan's syndrome causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Iqra Qamar M.D.[2]

Overview

Common causes of Sheehan's syndrome are including massive hemorrhage, hypotension during pregnancy, vascular compression, and vascular occlusion (thrombosis, DIC). Less common causes are including vascular insufficiency due to coronary artery bypass grafting (CABG) in older patients and snake bites (Russell's viper bites).

Sheehan's syndrome may be caused by the followings:

Less common causes of Sheehan's syndrome are including:

Cardiovascular	Hypotension, Vascular compression, Hemorrhage
Chemical/Poisoning	Snake bites
Dental	No underlying causes
Dermatologic	No underlying causes
Drug Side Effect	No underlying causes
Ear Nose Throat	No underlying causes
Endocrine	No underlying causes
Environmental	No underlying causes
Gastroenterologic	No underlying causes
Genetic	No underlying causes
Hematologic	Thrombosis, DIC
Iatrogenic	No underlying causes
Infectious Disease	No underlying causes
Musculoskeletal/Orthopedic	No underlying causes
Neurologic	No underlying causes
Nutritional/Metabolic	No underlying causes
Obstetric/Gynecologic	PPH, Traumatic birth delivery
Oncologic	No underlying causes
Ophthalmologic	No underlying causes
Overdose/Toxicity	No underlying causes
Psychiatric	No underlying causes
Pulmonary	No underlying causes
Renal/Electrolyte	No underlying causes
Rheumatology/Immunology/Allergy	Autoimmunity
Sexual	No underlying causes
Trauma	Traumatic delivery
Urologic	No underlying causes
Miscellaneous	No underlying causes

↑ Matsuzaki S, Endo M, Ueda Y, Mimura K, Kakigano A, Egawa-Takata T, Kumasawa K, Yoshino K, Kimura T (2017). "A case of acute Sheehan's syndrome and literature review: a rare but life-threatening complication of postpartum hemorrhage". BMC Pregnancy Childbirth. 17 (1): 188. doi:10.1186/s12884-017-1380-y. PMC 5471854. PMID 28615049.
↑ Davies JS, Scanlon MF (1998). "Hypopituitarism after coronary artery bypass grafting". BMJ. 316 (7132): 682–4. PMC 1112681. PMID 9522796.
↑ Antonypillai CN, Wass JA, Warrell DA, Rajaratnam HN (2011). "Hypopituitarism following envenoming by Russell's vipers (Daboia siamensis and D. russelii) resembling Sheehan's syndrome: first case report from Sri Lanka, a review of the literature and recommendations for endocrine management". QJM. 104 (2): 97–108. doi:10.1093/qjmed/hcq214. PMID 21115460.