Toxic Adenoma epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]

Overveiw

The prevalence rates of toxic adenoma is 5-7% and 1-2% of all hyperthyroid cases in women and men respectively.

Epidemiology

Prevalance

• Toxic adenoma prevalence is inversely related to a population’s dietary iodine sufficiency.
• In women and men, the prevalence rate of toxic adenoma is 5-7% and 1-2%, respectively.

Demographics

Age

• The incidence of toxic adenoma increases with age; the median age at diagnosis is 50 years.
• Toxic adenoma is more commonly seen in 56.5% of patients over 60 years but in only 12.5% of the younger patients.

Race

There is no racial predilection to toxic adenoma.

Gender

• Similar to any thyroid disease females are more commonly affected by toxic adenoma than males.
• In women and men, the prevalence rate of palpable nodules is 5-7% and 1-2%, respectively.
• The female-to-male ratio was 14.9:1 for nontoxic AFTNs and 5.9:1 for toxic AFTN patients