Zollinger-Ellison syndrome CT

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Aravind Reddy Kothagadi M.B.B.S[2] Mohamad Alkateb, MBBCh [3]

Overview

Abdominal CT scan may be helpful in the diagnosis of Zollinger-Ellison syndrome caused by gastrinoma. Gastrinomas are frequently multiple and often extrapancreatic (90% located in the gastrinoma triangle). Thus, they can be difficult to locate. For this reason, multiphase contrast enhanced thin slice cross-sectional imaging is ideal.[1] Findings on Abdominal CT scan suggestive of gastrinoma include clearly defined, well-enhanced mass.

Abdominal CT

  • Abdomen CT axial (A) and coronal (B) images showing a 2.7×2.4-cm, lobulated, enhancing lesion at the pancreas head (open arrow). [2]
Abdomen CT axial (A) and coronal (B) images. Yang RH, Chu YK, CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0 [2]


  • Findings on abdominal CT scan suggestive of gastrinomas include a clearly defined and well-enhanced mass.
  • Abdominal CT scan can be used to confirm the location of the cancer and to detect distant metastasis.
Abdominal CT scan showing a 3 × 2 cm, well-defined, uniformly enhanced mass adjacent to the duodenal loop. Lee WS, Koh YS, Kim JC, CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0 [3]

References

  1. Radiographic Features of Gastrinoma.Dr Frank Gaillard et al. Radiopaedia.org 2015. http://radiopaedia.org/articles/gastrinoma
  2. 2.0 2.1 Yang RH, Chu YK (2015). "Zollinger-Ellison syndrome: Revelation of the gastrinoma triangle". Radiol Case Rep. 10 (1): 827. doi:10.2484/rcr.v10i1.827. PMC 4921170. PMID 27408649.
  3. Lee WS, Koh YS, Kim JC, et al. Zollinger-Ellison syndrome associated with neurofibromatosis type 1: a case report. BMC Cancer. 2005;5:85.

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