Hypoparathyroidism epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

  • In Denmark, the incidence of postsurgical hypoparathyroidism is approximately 0.8 per 100,000 person-years. In United States, the prevalence of hypoparathyroidism is approximately 37 per 100,000 person-years. Majority of patients with hypoparathyroidism are 45 years or older. The women to men ratio is approximately 3 to 1.

Epidemiology and Demographics

Incidence

  • In Denmark, the incidence of postsurgical hypoparathyroidism is approximately 0.8 per 100,000 person-years.[1]

Prevalence

  • In United States, the prevalence of hypoparathyroidism is approximately 37 per 100,000 person-years.[2]
  • In Denmark, the prevalence of postsurgical hypoparathyroidism is approximately 22 per 100,000 person-years.[2]
  • In Denmark, the prevalance of nonsurgical hypoparathyroidism is approximately 2.3 per 100,000 person-years.[3]
  • In Japan, the prevalence of idiopathic hypoparathyroidism ranges from a low of 55 per 100,000 persons to a high of 88 per 100,000 persons with an average prevalence of 72 per 100,000 persons.[4]
  • In Japan, the prevalence of pseudohypoparathyroidism ranges from a low of 26 per 100,000 persons to a high of 42 per 100,000 persons with an average prevalence of 34 per 100,000 persons.[4]

Age

  • Majority of patients with hypoparathyroidism are 45 years or older.[5]

Gender

  • Women are more commonly affected by hypoparathyroidism than men. The women to men ratio is approximately 3 to 1.[5]

References

  1. Underbjerg L, Sikjaer T, Mosekilde L, Rejnmark L (2013). "Cardiovascular and renal complications to postsurgical hypoparathyroidism: a Danish nationwide controlled historic follow-up study". J Bone Miner Res. 28 (11): 2277–85. doi:10.1002/jbmr.1979. PMID 23661265.
  2. 2.0 2.1 Clarke BL, Brown EM, Collins MT, Jüppner H, Lakatos P, Levine MA, Mannstadt MM, Bilezikian JP, Romanischen AF, Thakker RV (2016). "Epidemiology and Diagnosis of Hypoparathyroidism". J. Clin. Endocrinol. Metab. 101 (6): 2284–99. doi:10.1210/jc.2015-3908. PMC 5393595. PMID 26943720.
  3. Underbjerg L, Sikjaer T, Mosekilde L, Rejnmark L (2015). "The Epidemiology of Nonsurgical Hypoparathyroidism in Denmark: A Nationwide Case Finding Study". J. Bone Miner. Res. 30 (9): 1738–44. doi:10.1002/jbmr.2501. PMID 25753591.
  4. 4.0 4.1 Nakamura Y, Matsumoto T, Tamakoshi A, Kawamura T, Seino Y, Kasuga M, Yanagawa H, Ohno Y (2000). "Prevalence of idiopathic hypoparathyroidism and pseudohypoparathyroidism in Japan". J Epidemiol. 10 (1): 29–33. PMID 10695258.
  5. 5.0 5.1 Powers J, Joy K, Ruscio A, Lagast H (2013). "Prevalence and incidence of hypoparathyroidism in the United States using a large claims database". J. Bone Miner. Res. 28 (12): 2570–6. doi:10.1002/jbmr.2004. PMID 23737456.

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