Silent thyroiditis other diagnostic studies

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De Quervain's thyroiditis Microchapters

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Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating De Quervain's thyroiditis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications, and Prognosis

Diagnosis

Diagnostic Criteria

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

Chest X Ray

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary prevention

Secondary prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]

Overview

The histological analysis in de Quervain's thyroiditis may show the destruction of the follicular epithelium, loss of the follicular integrity, and infiltration of inflammatory cells. Fine needle aspiration cytology helps to differentiate between the benign and malignant nodules.

Other Diagnostic Studies

Microscopic Pathology

Microscopic findings suggesting de Quervain's thyroiditis are as followings:[1]

  • Lymphoid follicles
  • Lymphocytic (T and B cells) infiltration
  • Presence of giant cells
  • Destruction of the follicular epithelium
  • Loss of the follicular integrity


Fine needle aspiration cytology

Fine needle aspiration is usually done under ultrasound guidance and the sample is sent for cytology. It helps to differentiate benign thyroid nodules from the malignant lesions.[2]


References

  1. Mizukami Y, Michigishi T, Hashimoto T, Tonami N, Hisada K, Matsubara F, Takazakura E (1988). "Silent thyroiditis: a histologic and immunohistochemical study". Hum. Pathol. 19 (4): 423–31. PMID 3284807.
  2. "Thyroiditis — NEJM".


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