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Differentials

Familial hypocalciuric hypercalcemia should be differentiated from other causes of hypercalcemia. Causes of hypercalcemia include:

Parathyroid-related

Hyperparathyroidism

-Primary hyperparathyroidism

-Secondary hyperparathyroidism

-Tertiary hyperparathyroidism

Non-parathyroid related

-Malignancy

-Humoral hypercalcemia of malignancy

-Osteolytic tumors

-Production of calcitriol by tumors

-Ectopic parathyroid hormone production

Medication-induced

-Thiazide diuretics

-Lithium

Other

-Nutritional

-Milk-alkali syndrome

-Vitamin D toxicity

-Granulomatous disease

-Sarcoidosis

-Surgical

-Immobilization