Myxedema coma history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]

History

• History of thyroid disease
• History of radioiodine therapy or thyroidectomy,
• Thyroid hormone therapy that was inappropriately discontinued

Symptoms

Symptoms of myxedema coma can be summarized in the following table:

Organ system involved	Manifestations
CNS	Lethargy Poor memory Cognitive dysfunction Depression Psychosis Hypothermia Focal or generalized seizures
Cardiovascular	SOB Chest pain
Pulmonary
Gastro-intestinal	Anorexia Nausea Abdominal pain Constipation
Renal and electrolyte	Bladder atony with urinary retention
Systemic	Presence of normal temperature in myxedema indicates presence of infection