Marburg hemorrhagic fever natural history, complications and prognosis

	Marburg hemorrhagic fever Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief:

Overview

Case fatality rates in Marburg hemorrhagic fever outbreaks have ranged from 23% to 90%.


Marburg Hemorrhagic Fever: Symptoms and Disease Progression
Generalisation Phase (Day 1 to Day 5)	Fever Headache Chills Myalgia Malaise Fatigue Nausea Vomiting Diarrhoea Abdominal Pain Conjunctivitis Rash Pharyngitis
Early Organ Phase (Day 6 to Day 13)	Fever Bloody Diarrhoea(Malena) Hematemesis Exanthema Petechiae/Ecchymoses Muscosal hemorrhage Visceral hemorrhage Dyspnea Conjunctival injection Edema Apathy/Depression Irritability/Aggression
Late Organ or Convalescence Phase (Day 14 to Day 21)	Fever Obtundation Dementia Coma Convulsions Diffuse coagulopathy Metabolic disturbances Shock Myalgia Arthralgia Hepatitis Asthenia Ocular disease Psychosis Social separation