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- Zenker's diverticula (ZD) is thought to be as a result of motor abnormalities of the esophagus.
- ZD emerge from a defect within the Killian's triangle that's a natural place for the weak point of the muscular wall of the hypopharynx.
- Killian's triangle is formed by the oblique fibers of the inferior pharyngeal constrictor muscle and the cricopharyngeal sphincter.
- Chronic strain on the Killian's triangle leads to an Evagination of the sphincter, which may be because of causes:
● High pressures in the food bolus in the course of swallowing ● Difficulty in swallowing because of abnormalities of the upper esophageal sphincter (UES)
- The consequences of numerous studies illustrate the kinds of observations made in patients with ZD:
- a variety of situations predisposing to herniation within Killian's triangle, inclusive of atypical esophageal motility, esophageal shortening, or disorders related to altered u.s.function.
- increased intrabolus pressures found in patients with ZD can be secondary to impaired bolus passage in combination with or as a result of gastroesophageal reflux disease.
- An unanswered question is how spasms of UES provoked by acid reflux should cause improved intrabolus pressures during swallowing, given that swallowing is often distinct from episodes of acid reflux disorder.