Ameloblastoma epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]
Overview
The incidence of ameloblastoma is approximately 1.96, 1.20, 0.18, and 0.44 per 100,000 for black males, black females, white males, and white females respectively worldwide. Ameloblastoma affects men and women equally. There is no racial predilection to the ameloblastoma. Ameloblastoma usually occur in middle age group i.e. 20-40 years: the median age at diagnosis is 39 years. [1][2]
Epidemiology and Demographics
Ameloblastoma although rare, is the most common odontogenic tumor accounting for 1% of all oral tumors and around 18% of all odontogenic tumors. They are rare in children. Approximately, 8.7% - 15% of all ameloblastomas occur in children. Ameloblastoma occurs in all areas of jaws, but the mandible is the most commonly affected area i.e. more than 80% of cases are seen here. Within the mandible, the area commonly involved is near the angle of the mandible in the region of the 3rd molar tooth (the molar angle ramus area). It is involved three times more commonly than are anterior and premolar regions combined. Although benign, it is a locally aggressive neoplasm with a high rate of recurrence.[1]
Incidence
The annual incidence of ameloblastoma is approximately 1.96, 1.20, 0.18, and 0.44 per 100,000 for black males, black females, white males, and white females respectively worldwide.
Gender
Ameloblastoma affects men and women equally. Although, women tend to be 4 years younger than men when tumors first occur and tumors appear to be larger in females.[2]
Race
There is no racial predilection to the ameloblastoma. However, there is conflicting evidence on the incidence rates in different races. Although some reports claim an increased incidence of ameloblastoma in black individuals, a large study identifies Asians as the population with greatest number of affected patients. Ameloblastoma is by far the most common unequivocal odontogenic neoplasm in all ethnic groups, representing approximately 1% of head and neck neoplasms in Europe and the USA, some studies claim that it has the highest incidence in Afro-Caribbean populations.[3]
Age
They are slow growing and tend to present in the 3rd to 5th decades of life. Ameloblastoma usually occur in middle age group i.e. 20-40 years: the median age at diagnosis is 39 years. Maxillary and extraosseous ameloblastoma commonly affects individuals in a slightly older age group while unicystic and granular cell ameloblastoma occur in a younger age group. The average age of unicystic ameloblastoma is 10.8 years.
References
- ↑ 1.0 1.1 Ameloblastoma. Wikipedia(2015) https://en.wikipedia.org/wiki/Ameloblastoma Accessed on December 25, 2015
- ↑ 2.0 2.1 Toledo-Pereyra LH, Bergren CT (1987). "Liver preservation techniques for transplantation". Artif Organs. 11 (3): 214–23. PMID 3304226.
- ↑ Morgan, Peter R. (2011). "Odontogenic tumors: a review". Periodontology 2000. 57 (1): 160–176. doi:10.1111/j.1600-0757.2011.00393.x. ISSN 0906-6713.