Plummer-Vinson syndrome historical perspective

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:

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Overview

The historical perspective associated with Plummer-Vinson syndrome is as below:^[1]

In the year 1912, Henry Plummer an American internist, was the first to describe Plummer-Vinson syndrome in a case series of patients with long-standing iron deficiency anemia, dysphagia and spasm of the upper esophagus without anatomic stenosis in his article "Diffuse dilatation of the esophagus without anatomic stenosis"
In the year 1919, Porter Paisley Vinson an American surgeon at the Mayo Clinic further described Plummer-Vinson syndrome in his article "A case of cardiospasm with dilatation and angulation of the esophagus." He reported a case of angulation of esophagus and attributed his findings to be consistent with the those described by Henry Plummer.

In the year 1919, Donald Ross Paterson a British otolaryngologist described Plummer-Vinson syndrome in his article "A clinical type of dysphagia"
In the year 1919, Adam Brown Kelly an ENT surgeon in London described Plummer-Vinson syndrome in his article "Spasm at the entrance of the esophagus".

The association between [important risk factor/cause] and [disease name] was made in/during [year/event].
In [year], [scientist] was the first to discover the association between [risk factor] and the development of [disease name].
In [year], [gene] mutations were first implicated in the pathogenesis of [disease name].

reported another case of 'angulation' of the esophagus and attributed the first description of this entity to the earlier report of Plummer

There have been several outbreaks of [disease name], which are summarized below:

In [year], [diagnostic test/therapy] was developed by [scientist] to treat/diagnose [disease name].

↑ Ormerod FC (1966). "Plummer-Vinson or Paterson-Brown Kelly. Priority, precedence or prestige?". J Laryngol Otol. 80 (9): 894–901. PMID 5332006.