Whipple's disease laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Some patients with [Whipple's disease] may have abnormal hematological findings and elevated acute phase reactants , which is usually suggestive of the disease. Biopsy of affected tissue is important for making the diagnosis.

Laboratory Findings

• An elevated level of acute phase reactants is seen in [Whipples disease].
• Hematological findings include:
  • anemia
  • leukocytosis
  • thrombocytosis/thrombocytopenia

• Laboratory evidence of malabsorption may be seen.