Sandbox: malabsorption
Abbreviations: WBC: White blood cells; Plt: Platelets, Hgb: Hemoglobin, IgE: Immunoglobulin E, IgA: Immunoglobulin A
Cause | Peak age of onset | History | Physical exam | Lab findings | Additional findings | Cause/Pathogenesis | Gold standard diagnosis | ||||||||
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Fever | Abdominal pain | Diarrhea | Weight loss | ||||||||||||
Watery | Fatty | WBC | Hgb | Plt | Other lab findings | ||||||||||
Whipple's disease | 40-60 | +/- | + | + | + | + |
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↓ | ↓ | ↓/↑ |
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Celiac disease | Childhood
Adult |
- | + | +/- | +/- | + | - | ↓ | - |
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Cystic fibrosis | Childhood
Adult |
+ | + | - | + | + |
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Crohns disease | Young adults
(20th) |
+ | + | + | + | + | ↑ | ↓ |
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Irritable bowel syndrome | 30-50 | - | +/- | +/- | +/- | - |
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- | - | - |
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VIPoma | 30-50 | - | + | + | + | + |
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Zollinger-Ellison syndrome) | 20-50 |
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Lactose intolerance | Any age | + |
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Allergic enteropathy/Food protein-induced enterocolitis syndrome (FPIES) | Infancy | + | - | +/- | + | Stool examination:
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Eosinophilic gastroenteritis | 30th | + | - | +/- | + |
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Primary bile acid malabsorption | Childhood Adolescents | + | +/- | + | +/- | - |
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Abetalipoproteinemia | Infancy | - | + | + | + |
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Microscopic colitis | 60th | + | - | + | + |
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Hyperthyroidism | Any age | + | - | + | +/- |
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Grain allergy | Childhood | - | + | + | - | + |
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