Mallory-Weiss syndrome natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamed Diab, MD [2]

Natural History

Mallory-Weiss tears heal quickly in the absence of portal hypertensive. Patients should be assessed for hemodynamic stability and determine the need for fluid resuscitation and/or blood transfusion.

Complications

• Hemorrhage
• Organ ischemia and infarction

Prognosis

• Repeated bleeding is uncommon and the outcome is usually good. Cirrhosis of the liver and problems with blood clotting make future bleeding episodes more likely to occur.

• Patients do not require repeat endoscopic evaluation to document healing.
• Approximately 40% to 70% of patients with bleeding Mallory-Weiss syndrome require blood transfusions.
• The mortality rate is approximately 5% and depends on the age and the presence of coexisting medical conditions.

References

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