Budd-Chiari syndrome history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

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History and Symptoms

History

The hallmark of Budd-Chiari syndrome is a triad of right upper quadrant abdominal pain, ascites, and hepatomegaly. A positive history of associated risk factors like myeloproliferative disorders, malignancy, paroxysmal nocturnal hemoglobinuria, antiphospholipid syndrome, factor V leiden mutation, infections and benign liver lesions, oral contraceptives and pregnancy, hypercoagulable states, Behçet's syndrome, membranous webs.

Common Symptoms

• Symptoms of Budd-Chiari syndrome include:
  • Fever
  • Abdominal pain
  • Abdominal distension from ascites
  • Lower extremity edema
  • Jaundice
  • Gastrointestinal bleeding from varices or portal hypertensive gastropathy
  • hepatic encephalopathy.

Less Common Symptoms

• Patients with subacute or chronic Budd-Chiari syndrome may be asymptomatic.