Mucoepidermoid carcinoma staging

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]

Overview

According to the American Joint Committee on Cancer (AJCC) 7th edition, there are 6 stages of mucoepidermoid carcinoma based on the tumor size and node invasion. Each stage is assigned a letter and a number that designate the tumor size and node invasion.

Staging

• According to the American Joint Committee on Cancer (AJCC) 7th edition, there are 6 stages of mucoepidermoid carcinoma based on the tumor size and node invasion. Each stage is assigned a letter and a number that designate the tumoral size and node invasion. The table below summarizes the American Joint Committee on Cancer (AJCC) staging classification.

Mucoepidermoid carcinoma staging Adapted from American Joint Committee on Cancer (AJCC). 1998
Tumor	T1 - 2cm or less w/o extraparenchymal extension
	T2 - >2cm but not greater than 4cm; and w/o extraparenchymal extension
	T3 - >4cm or with extraparenchymal extension
	T4a - invades skin,mandible, ear canal or facial nerve
	T4b - invades skull base, pterygoid plates or encases carotid
Nodes	NX - Cannot be assessed
	N0 - No regional lymph nodes metastasis
	N1 - Single ipsilateral lymph node, <= 3cm in greatest dimension
	N2 N2a - Single ipsilateral lymph node, 3-6 cm in greatest dimension N2b - Multiple ipsilateral lymph nodes, <= 6cm in greatest dimension N2c - Bilateral or contralateral lymph nodes, <= 6cm in greatest dimension
	N3 - Lymph node(s) >6 cm in greatest dimension
Overall stage	I - T1 N0
	II - T2 N0
	III - T3 N0-1, or T1-3 N1
	IVA - T4a N0-2, or T1-4a
	IVB - T4b N0-3, or T1-4b N3
	IVC - M1