Gastrointestinal stromal tumor causes

Gastrointestinal stromal tumor Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]

Overview

There are no established causes for gastrointestinal stromal tumor.

Causes

Most GISTs are sporadic. Less than 5% occur as part of hereditary, familial, or idiopathic multitumor syndromes.

Common causes of gastrointestinal stromal tumor include mutation in c-Kit gene and PDGFRA gene.