Hemochromatosis epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Epidemiology and Demographics
Hemochromatosis is one of the most common inheritable genetic defects.[1]
Incidence:
- In 2016, the incidence of C282Y is estimated to be 5400 cases per 100,000.
- In 2016, the incidence of H63D is estimated to be 13500 cases per 100,000.
Prevalence:
- In 2017, the prevalence of Hemochromatosis was estimated to be from 500 case in 100000 individuals.
- The carrier state is estimated to be approximately 10000 in 100000.
Race:
- Prevalence of hemochromatosis is 6 times higher in white persons than in black persons.
- C282Y homozygotes account for 82-90% of clinical diagnoses of hereditary hemochromatosis among persons of northern European descent
- Irish have highest prevalence of hemochromatosis.
Countries: