Primary sclerosing cholangitis historical perspective

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dima Nimri, M.D. [2]

Overview

Due to the rarity of the disease, primary sclerosing cholangitis has not been well studied in the past and cases were reported as individual cases. The first case of primary sclerosing cholangitis was documented in 1924.

Historical Perspective

The following gives a historical perspective on primary sclerosing cholangitis:

• In 1877, Dr. Jean-Martin Charcot at the Salpêtrière hospital in Paris, France was the first to describe cholangitis as a triad of three symptoms: pain, fever, and jaundice.
• In 1924 the first case of primary sclerosing cholangitis was reported, followed by another case in 1925. Since the disease is rare, cases of primary sclerosing cholangitis were reported as individual cases.
• In 1971, the first review article on primary sclerosing cholangitis was published.

References

de:Cholangitis sv:Primär skleroserande kolangit

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