Constipation natural history, complications and prognosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:
Overview
If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
OR
Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].
OR
Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
Natural History, Complications, and Prognosis
Natural History
- The symptoms of constipation usually can develop in the different decades of life, and start with symptoms such as bloating, mucos passage, and abdominal pain.
- Then the symptoms severed by hardened stool formation which is contributed by straining and inability to pass the stool, needed manual evacuation.
- If left untreated, patients with constipation may progress to develop rectal bleeding, colon perforation, and ultimately colorectal diverticulum and cancer.[1]
Complications
- Common complications of chronic constipation include:[2]
Prognosis
- Prognosis is generally excellent, and the survival rate of patients with constipation is approximately 100%.
- The presence of palpable rectal mass and also female gender is associated with a particularly good prognosis among patients with constipation.[3]
- The colonic transit time (CTT) more than 100 hours is associated with a particularly poor prognosis among patients with constipation.[4][5][6]
References
- ↑ Choung RS, Locke GR, Rey E, Schleck CD, Baum C, Zinsmeister AR; et al. (2012). "Factors associated with persistent and nonpersistent chronic constipation, over 20 years". Clin Gastroenterol Hepatol. 10 (5): 494–500. doi:10.1016/j.cgh.2011.12.041. PMC 3589972. PMID 22289877.
- ↑ Cheng M, Ghahremani S, Roth A, Chawla SC (2016). "Chronic Constipation and Its Complications: An Interesting Finding to an Otherwise Commonplace Problem". Glob Pediatr Health. 3: 2333794X16648843. doi:10.1177/2333794X16648843. PMC 4905124. PMID 27336021.
- ↑ de Lorijn F, van Wijk MP, Reitsma JB, van Ginkel R, Taminiau JA, Benninga MA (2004). "Prognosis of constipation: clinical factors and colonic transit time". Arch Dis Child. 89 (8): 723–7. doi:10.1136/adc.2003.040220. PMC 1720034. PMID 15269069.
- ↑ Benninga MA, Büller HA, Tytgat GN, Akkermans LM, Bossuyt PM, Taminiau JA (1996). "Colonic transit time in constipated children: does pediatric slow-transit constipation exist?". J. Pediatr. Gastroenterol. Nutr. 23 (3): 241–51. PMID 8890073.
- ↑ Verduron A, Devroede G, Bouchoucha M, Arhan P, Schang JC, Poisson J, Hémond M, Hébert M (1988). "Megarectum". Dig. Dis. Sci. 33 (9): 1164–74. PMID 3409803.
- ↑ Benninga MA, Büller HA, Heymans HS, Tytgat GN, Taminiau JA (1994). "Is encopresis always the result of constipation?". Arch. Dis. Child. 71 (3): 186–93. PMC 1029969. PMID 7979489.