Cirrhosis MRI
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Vishnu Vardhan Serla M.B.B.S. [2]
Overview
The use of magnetic resonance imaging (MRI) as a diagnostic test for cirrhosis is uncertain. MRI sometimes differentiates among regenerating or dysplastic nodules and hepatocellular carcinoma, it is best used as a follow-up study to determine whether lesions have changed in appearance and size.
MRI
Role of MRI in cirrhosis:[1][2][3][4][5][6][7]
- The role of magnetic resonance imaging (MRI) in the diagnosis of cirrhosis is unclear.
- The use of MRI is limited by expense, patient intolerability, and the ability to obtain information provided by MRI through other means.
- MRI differentiates among regenerating or dysplastic nodules and hepatocellular carcinoma by accurately determining the nature of focal lesions.[1][2][8][9]
- MRI is used as a follow-up study to determine whether lesions have changed in appearance and size.
- MRI may accurately diagnose cirrhosis and determines disease severity.[10][11][12]
- Decreased signal intensity on MRI may also reveal an iron overload and provides an estimate of the hepatic iron concentration.
MRA
- Magnetic resonance angiography (MRA) may be used to assess portal hypertensive changes including volume and direction of blood flow in the portal vein.
- MR angiography is more sensitive than ultrasonography in diagnosing complications of cirrhosis such as portal vein thrombosis.[13]
- The use of MRA is limited by its expense and the ability of routine ultrasonography with Doppler to obtain adequate information for the diagnosis of cirrhosis and presence of complications.
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References
- ↑ 1.0 1.1 Bonkovsky HL, Rubin RB, Cable EE, Davidoff A, Rijcken TH, Stark DD (1999). "Hepatic iron concentration: noninvasive estimation by means of MR imaging techniques". Radiology. 212 (1): 227–34. doi:10.1148/radiology.212.1.r99jl35227. PMID 10405746.
- ↑ 2.0 2.1 Ito K, Mitchell DG, Hann HW, Kim Y, Fujita T, Okazaki H, Honjo K, Matsunaga N (1999). "Viral-induced cirrhosis: grading of severity using MR imaging". AJR Am J Roentgenol. 173 (3): 591–6. doi:10.2214/ajr.173.3.10470885. PMID 10470885.
- ↑ Ernst O, Sergent G, Bonvarlet P, Canva-Delcambre V, Paris JC, L'Herminé C (1997). "Hepatic iron overload: diagnosis and quantification with MR imaging". AJR Am J Roentgenol. 168 (5): 1205–8. doi:10.2214/ajr.168.5.9129412. PMID 9129412.
- ↑ Gandon Y, Guyader D, Heautot JF, Reda MI, Yaouanq J, Buhé T, Brissot P, Carsin M, Deugnier Y (1994). "Hemochromatosis: diagnosis and quantification of liver iron with gradient-echo MR imaging". Radiology. 193 (2): 533–8. doi:10.1148/radiology.193.2.7972774. PMID 7972774.
- ↑ Ito K, Mitchell DG, Gabata T, Hussain SM (1999). "Expanded gallbladder fossa: simple MR imaging sign of cirrhosis". Radiology. 211 (3): 723–6. doi:10.1148/radiology.211.3.r99ma31723. PMID 10352597.
- ↑ Ito K, Mitchell DG, Hann HW, Outwater EK, Kim Y, Fujita T, Okazaki H, Honjo K, Matsunaga N (1998). "Progressive viral-induced cirrhosis: serial MR imaging findings and clinical correlation". Radiology. 207 (3): 729–35. doi:10.1148/radiology.207.3.9609897. PMID 9609897.
- ↑ Finn JP, Kane RA, Edelman RR, Jenkins RL, Lewis WD, Muller M, Longmaid HE (1993). "Imaging of the portal venous system in patients with cirrhosis: MR angiography vs duplex Doppler sonography". AJR Am J Roentgenol. 161 (5): 989–94. doi:10.2214/ajr.161.5.8273643. PMID 8273643.
- ↑ Choi D, Kim SH, Lim JH, Cho JM, Lee WJ, Lee SJ, Lim HK (2001). "Detection of hepatocellular carcinoma: combined T2-weighted and dynamic gadolinium-enhanced MRI versus combined CT during arterial portography and CT hepatic arteriography". J Comput Assist Tomogr. 25 (5): 777–85. PMID 11584240.
- ↑ Qayyum A, Goh JS, Kakar S, Yeh BM, Merriman RB, Coakley FV (2005). "Accuracy of liver fat quantification at MR imaging: comparison of out-of-phase gradient-echo and fat-saturated fast spin-echo techniques--initial experience". Radiology. 237 (2): 507–11. doi:10.1148/radiol.2372040539. PMID 16244259.
- ↑ Ito K, Mitchell DG, Hann HW, Kim Y, Fujita T, Okazaki H, Honjo K, Matsunaga N (1999). "Viral-induced cirrhosis: grading of severity using MR imaging". AJR. American Journal of Roentgenology. 173 (3): 591–6. PMID 10470885. Retrieved 2012-09-06. Unknown parameter
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ignored (help) - ↑ Ito K, Mitchell DG, Gabata T, Hussain SM (1999). "Expanded gallbladder fossa: simple MR imaging sign of cirrhosis". Radiology. 211 (3): 723–6. PMID 10352597. Retrieved 2012-09-06. Unknown parameter
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ignored (help) - ↑ Ito K, Mitchell DG, Hann HW, Outwater EK, Kim Y, Fujita T, Okazaki H, Honjo K, Matsunaga N (1998). "Progressive viral-induced cirrhosis: serial MR imaging findings and clinical correlation". Radiology. 207 (3): 729–35. PMID 9609897. Retrieved 2012-09-06. Unknown parameter
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ignored (help) - ↑ Finn JP, Kane RA, Edelman RR, Jenkins RL, Lewis WD, Muller M, Longmaid HE (1993). "Imaging of the portal venous system in patients with cirrhosis: MR angiography vs duplex Doppler sonography". AJR. American Journal of Roentgenology. 161 (5): 989–94. PMID 8273643. Retrieved 2012-09-06. Unknown parameter
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ignored (help)