Non-alcoholic fatty liver disease

	Non-Alcoholic Fatty Liver Disease Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]

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Synonyms and keywords: NASH, NAFLD, non alcoholic steatohepatitis

Overview

The symptoms of NAFLD usually develop in the fourth decade of life.
With the raising concern of obesity and metabolic syndrome NAFLD is becoming the most common liver disease in the world.
Our understanding of NAFLD natural history is evolving with extensive research and we can classify NAFLD further by prospectively collecting the data with well defined and well designed studies. ^[1]
If left untreated, Patients with NAFLD may progress to develop NASH which is a more serious complication.

Prognosis is generally variable with NAFLD patients.
Depending on the NAFLD Activity Score (NAS) of the NAFLD at the time of diagnosis, the prognosis may vary.
The presence of fibrosis in NAFLD patients is associated with a particularly poor prognosis.^[3]
[Subtype of disease/malignancy] is associated with the most favorable prognosis.
The prognosis varies with the [characteristic] of tumor; [subtype of disease/malignancy] have the most favorable prognosis.