Portal vein thrombosis risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Farima Kahe M.D. [2]
Overview
Common risk factors in the development of portal vein thrombosis include cirrhosis, pancreatitis, duodenal ulcer, cholecystitis, Crohn’s disease, ulcerative colitis and cholecystectomy, diverticulitis and appendicitis . Less common risk factors in the development of portal vein thrombosis include oral contraceptives, pregnancy or puerperium, and hyperhomocysteinemia.
Risk Factors
- Common risk factors in the development of portal vein thrombosis include cancer of cirrhosis, pancreatitis, duodenal ulcer, cholecystitis, Crohn’s disease, ulcerative colitis and cholecystectomy.
Common Risk Factors
- Common risk factors in the development of portal vein thrombosis include:[1][2][3][4][5][6]
- Cirrhosis
- Focal inflammatory lesions
- Neonatal omphalitis, umbilical vein catheterization
- Diverticulitis
- Appendicitis
- Pancreatitis
- Duodenal ulcer
- Cholecystitis
- Tuberculous lymphadenitis
- Crohn’s disease, ulcerative colitis
- Cytomegalovirus hepatitis
- Injury to the portal venous system
- Splenectomy
- Colectomy, gastrectomy
- Cholecystectomy
- Liver transplantation
- Abdominal trauma
- Surgical portosystemic shunting
- Iatrogenic (fine needle aspiration of abdominal masses etc.)
- Preserved liver function with precipitating factors (splenectomy, surgical portosystemic shunting, TIPS dysfunction, thrombophilia)
- Advanced disease in the absence of obvious precipitating factors
- Less common risk factors in the development of portal vein thrombosis include:[5][7][8]
References
- ↑ Webster GJ, Burroughs AK, Riordan SM (2005). "Review article: portal vein thrombosis -- new insights into aetiology and management". Aliment. Pharmacol. Ther. 21 (1): 1–9. doi:10.1111/j.1365-2036.2004.02301.x. PMID 15644039.
- ↑ Ponziani FR, Zocco MA, Campanale C, Rinninella E, Tortora A, Di Maurizio L, Bombardieri G, De Cristofaro R, De Gaetano AM, Landolfi R, Gasbarrini A (2010). "Portal vein thrombosis: insight into physiopathology, diagnosis, and treatment". World J. Gastroenterol. 16 (2): 143–55. PMC 2806552. PMID 20066733.
- ↑ Wang JT, Zhao HY, Liu YL (2005). "Portal vein thrombosis". HBPD INT. 4 (4): 515–8. PMID 16286254.
- ↑ Hoekstra J, Janssen HL (2009). "Vascular liver disorders (II): portal vein thrombosis". Neth J Med. 67 (2): 46–53. PMID 19299846.
- ↑ 5.0 5.1 Sobhonslidsuk A, Reddy KR (2002). "Portal vein thrombosis: a concise review". Am. J. Gastroenterol. 97 (3): 535–41. doi:10.1111/j.1572-0241.2002.05527.x. PMID 11922544.
- ↑ Webster GJ, Burroughs AK, Riordan SM (2005). "Review article: portal vein thrombosis -- new insights into aetiology and management". Aliment. Pharmacol. Ther. 21 (1): 1–9. doi:10.1111/j.1365-2036.2004.02301.x. PMID 15644039.
- ↑ Denninger MH, Chaït Y, Casadevall N, Hillaire S, Guillin MC, Bezeaud A, Erlinger S, Briere J, Valla D (2000). "Cause of portal or hepatic venous thrombosis in adults: the role of multiple concurrent factors". Hepatology. 31 (3): 587–91. doi:10.1002/hep.510310307. PMID 10706547.
- ↑ Chawla Y, Duseja A, Dhiman RK (2009). "Review article: the modern management of portal vein thrombosis". Aliment. Pharmacol. Ther. 30 (9): 881–94. doi:10.1111/j.1365-2036.2009.04116.x. PMID 19678814.