QSOX1

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External IDsGeneCards: [1]
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Sulfhydryl oxidase 1 is an enzyme that in humans is encoded by the QSOX1 gene.[1][2][3]

This gene encodes a protein that contains domains of thioredoxin and ERV1, members of two long-standing gene families. The gene expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation. Two transcript variants encoding two different isoforms have been found for this gene.[3]

References

  1. Coppock DL, Cina-Poppe D, Gilleran S (Feb 1999). "The quiescin Q6 gene (QSCN6) is a fusion of two ancient gene families: thioredoxin and ERV1". Genomics. 54 (3): 460–8. doi:10.1006/geno.1998.5605. PMID 9878249.
  2. Coppock DL, Kopman C, Scandalis S, Gilleran S (Oct 1993). "Preferential gene expression in quiescent human lung fibroblasts". Cell Growth Differ. 4 (6): 483–93. PMID 8396966.
  3. 3.0 3.1 "Entrez Gene: QSCN6 quiescin Q6".

Further reading