IL17RD
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External IDs | GeneCards: [1] | ||||||
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Species | Human | Mouse | |||||
Entrez |
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Ensembl |
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Location (UCSC) | n/a | n/a | |||||
PubMed search | n/a | n/a | |||||
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Interleukin 17 receptor D is a protein that in humans is encoded by the IL17RD gene. [1]
Function
This gene encodes a membrane protein belonging to the interleukin-17 receptor (IL-17R) protein family. The encoded protein is a component of the interleukin-17 receptor signaling complex, and the interaction between this protein and IL-17R does not require the interleukin. The gene product also affects fibroblast growth factor signaling, inhibiting or stimulating growth through MAPK/ERK signaling. Alternate splicing generates multiple transcript variants encoding distinct isoforms.
References
- ↑ "Entrez Gene: Interleukin 17 receptor D". Retrieved 2016-04-17.
Further reading
- Kovalenko D, Yang X, Nadeau RJ, Harkins LK, Friesel R (2003). "Sef inhibits fibroblast growth factor signaling by inhibiting FGFR1 tyrosine phosphorylation and subsequent ERK activation". J. Biol. Chem. 278 (16): 14087–91. doi:10.1074/jbc.C200606200. PMID 12604616.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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