TRANK1

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Tetratricopeptide repeat and ankyrin repeat containing 1 is a protein that in humans is encoded by the TRANK1 gene. [1]

Disease Linkage

Through a Genome-wide association study, TRANK1 has been relationed with the Bipolar disorder.[2]

References

  1. "Entrez Gene: Tetratricopeptide repeat and ankyrin repeat containing 1". Retrieved 2014-06-22.
  2. "Genome-wide association study reveals two new risk loci for bipolar disorder". Nat Commun. 5: 3339. 2014. doi:10.1038/ncomms4339. PMID 24618891.

Further reading

  • Goes, F. S.; Hamshere, M. L.; Seifuddin, F; Pirooznia, M; Belmonte-Mahon, P; Breuer, R; Schulze, T; Nöthen, M; Cichon, S; Rietschel, M; Holmans, P; Zandi, P. P.; Craddock, N; Craddock, N; Potash, J. B. (2012). "Genome-wide association of mood-incongruent psychotic bipolar disorder". Translational Psychiatry. 2 (10): e180. doi:10.1038/tp.2012.106. PMC 3565814. PMID 23092984.
  • Chen, D. T.; Jiang, X; Akula, N; Shugart, Y. Y.; Wendland, J. R.; Steele, C. J.; Kassem, L; Park, J. H.; Chatterjee, N; Jamain, S; Cheng, A; Leboyer, M; Muglia, P; Schulze, T. G.; Cichon, S; Nöthen, M. M.; Rietschel, M; McMahon, F J; McMahon, F. J.; Kelsoe, J. R.; Greenwood, T. A.; Nievergelt, C. M.; McKinney, R; Shilling, P. D.; Schork, N. J.; Smith, E. N.; Bloss, C. S.; Nurnberger Jr, J. I.; Edenberg, H. J.; et al. (2013). "Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder". Molecular Psychiatry. 18 (2): 195–205. doi:10.1038/mp.2011.157. PMID 22182935.