ZBTB1

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Zinc finger and BTB domain containing 1 is a protein in humans that is encoded by the ZBTB1 gene. [1]

ZBTB1 is essential for the development of lymphocytes in mice: T cells are absent from ZBTB1 mutant mice, and numbers of B cells and natural killer cells are reduced .[2][3]

References

  1. "Entrez Gene: Zinc finger and BTB domain containing 1". Retrieved 2013-04-23.
  2. Siggs, O.M., Li, X., Xia, Y., and Beutler, B. (2012). ZBTB1 is a determinant of lymphoid development. J Exp Med 209, 19–27.
  3. Punwani, D., Simon, K., Choi, Y., Dutra, A., Gonzalez-Espinosa, D., Pak, E., Naradikian, M., Song, C.-H., Zhang, J., Bodine, D.M., et al. (2012). Transcription Factor Zinc Finger and BTB Domain 1 Is Essential for Lymphocyte Development. J Immunol 189, 1253–1264.

Further reading