ACSBG1

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Identifiers
Aliases
External IDs	GeneCards: [1]
Orthologs
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a
Wikidata
View/Edit Human

Acyl-CoA Synthetase, Bubblegum Family, member 1 (ACSBG1) is an enzyme that in humans is encoded by the ACSBG1 gene.

The protein encoded by this gene possesses long-chain acyl-CoA synthetase activity. It is thought to play a central role in brain very long-chain fatty acids metabolism and myelinogenesis. The conversion of long chain fatty acids into long chain acyl-CoAs in mice is catalysed by ACSBG1.

External links

• Human ACSBG1 genome location and ACSBG1 gene details page in the UCSC Genome Browser.

Further reading

• Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
• Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
• Moriya-Sato A, Hida A, Inagawa-Ogashiwa M, et al. (2001). "Novel acyl-CoA synthetase in adrenoleukodystrophy target tissues". Biochem. Biophys. Res. Commun. 279 (1): 62–8. doi:10.1006/bbrc.2000.3897. PMID 11112418.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Pei Z, Oey NA, Zuidervaart MM, et al. (2004). "The acyl-CoA synthetase "bubblegum" (lipidosin): further characterization and role in neuronal fatty acid beta-oxidation.". J. Biol. Chem. 278 (47): 47070–8. doi:10.1074/jbc.M310075200. PMID 12975357.
• Fraisl P, Forss-Petter S, Zigman M, Berger J (2004). "Murine bubblegum orthologue is a microsomal very long-chain acyl-CoA synthetase". Biochem. J. 377 (Pt 1): 85–93. doi:10.1042/BJ20031062. PMC 1223850. PMID 14516277.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Asheuer M, Bieche I, Laurendeau I, et al. (2005). "Decreased expression of ABCD4 and BG1 genes early in the pathogenesis of X-linked adrenoleukodystrophy". Hum. Mol. Genet. 14 (10): 1293–303. doi:10.1093/hmg/ddi140. PMID 15800013.