TUG1 (taurine upregulated gene 1) is a long non-coding RNA expressed in the retina and in the brain. It was first identified in a screen for genes upregulated by in developing retinal cells in response to taurine. It is required for the normal development of photoreceptors in the retina.[1]
↑Young TL, Matsuda T, Cepko CL (March 2005). "The noncoding RNA taurine upregulated gene 1 is required for differentiation of the murine retina". Curr. Biol. 15 (6): 501–12. doi:10.1016/j.cub.2005.02.027. PMID15797018.
Further reading
Bonaldo MF, Lennon G, Soares MB (1996). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID8889548.
Wang AG, Yoon SY, Oh JH, et al. (2006). "Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags". Biochem. Biophys. Res. Commun. 345 (3): 1022–32. doi:10.1016/j.bbrc.2006.04.175. PMID16712791.
Brandenberger R, Wei H, Zhang S, et al. (2004). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID15146197.
Ishiguro T, Nakajima M, Naito M, et al. (1996). "Identification of genes differentially expressed in B16 murine melanoma sublines with different metastatic potentials". Cancer Res. 56 (4): 875–9. PMID8631027.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID14702039.
