Non-alcoholic fatty liver disease MRI
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]
Overview
Abdominal MRI may be helpful in the diagnosis of non-alcoholic fatty liver disease. Findings on MRI suggestive of non-alcoholic fatty liver disease include quantification of the hepatic steatosis. MRI has a sensitivity of 96% and specificity of 93% in diagnosing NAFLD. However, it uses is limited because of the cost.
MRI
- Abdominal MRI may be helpful in the diagnosis of NAFLD.[1][2]
- Findings on MRI suggestive NAFLD include:
- Quantification of hepatic steatosis.[3][4]
- Drop in signal intensity in liver on the out-of-phase sequence, compatible with intra-cellular lipid deposition.
- MRI also helps longitudinal follow-up of patients with non-alcoholic fatty liver disease to check response to therapy
- Another kind of MRI is magnetic resonance spectroscopy (MRS) which reflects fat in the whole liver like triglycerides in a specific volume; and proton density fat fraction (PDFF).[5]
References
- ↑ "Nonalcoholic Fatty Liver Disease: Diagnosis and Management - American Family Physician".
- ↑ "Nonalcoholic Fatty Liver Disease: Diagnosis and Management - American Family Physician".
- ↑ Ligabue G, Besutti G, Scaglioni R, Stentarelli C, Guaraldi G (2013). "MR quantitative biomarkers of non-alcoholic fatty liver disease: technical evolutions and future trends". Quant Imaging Med Surg. 3 (4): 192–5. doi:10.3978/j.issn.2223-4292.2013.08.01. PMC 3759141. PMID 24040614.
- ↑ Lee SS, Park SH (2014). "Radiologic evaluation of nonalcoholic fatty liver disease". World J. Gastroenterol. 20 (23): 7392–402. doi:10.3748/wjg.v20.i23.7392. PMC 4064084. PMID 24966609.
- ↑ Di Martino M, Koryukova K, Bezzi M, Catalano C (2017). "Imaging Features of Non-Alcoholic Fatty Liver Disease in Children and Adolescents". Children (Basel). 4 (8). doi:10.3390/children4080073. PMC 5575595. PMID 28800087.