Alpha 1-antitrypsin deficiency x ray
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
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Overview
On chest Xray Alpha1-antitrypsin deficiency (AATD) emphysema presents as a hyperlucent appearance because healthy tissue has been destroyed.Affected regions also are described as oligemic because they lack the normal rich pattern of branching blood vessels.An unusual characteristic in alpha1-antitrypsin deficiency is found in about two thirds of PiZZ patients; the emphysema has a striking basilar distribution.In contrast, cigarette smoking is associated with more severe apical disease.
X Ray
On chest Xray Alpha1-antitrypsin deficiency (AATD) emphysema presents as:Parr DG, Stoel BC, Stolk J, Stockley RA (2004). "Pattern of emphysema distribution in alpha1-antitrypsin deficiency influences lung function impairment". Am. J. Respir. Crit. Care Med. 170 (11): 1172–8. doi:10.1164/rccm.200406-761OC. PMID 15306534.King MA, Stone JA, Diaz PT, Mueller CF, Becker WJ, Gadek JE (1996). "Alpha 1-antitrypsin deficiency: evaluation of bronchiectasis with CT". Radiology. 199 (1): 137–41. doi:10.1148/radiology.199.1.8633137. PMID 8633137.
- a hyperlucent appearance because healthy tissue has been destroyed.
- Affected regions also are described as oligemic because they lack the normal rich pattern of branching blood vessels.
- An unusual characteristic in alpha1-antitrypsin deficiency is found in about two thirds of PiZZ patients; the emphysema has a striking basilar distribution.
- In contrast, cigarette smoking is associated with more severe apical disease.
