Gallbladder cancer epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]
Overview
Around 80 t0 95% of biliary tract cancers are gallbladder cancers.Epidemiological research have recognized striking geographic and ethnic difference. An excessive incidence in American Indians and Southeast Asia, but pretty low some place else in the Americas and the arena.
Epidemiology and Demographics
Incidence
- The countries with high incidence have high mortality rate because mortality rate relatively follows incidence
- American Indian and Alaska Native people had the highest gallbladder cancer incidence.
Prevalence
- The incidence/prevalence of gallbladder cancer is approximately 21 per 100,000 cancer incidence and 75.8% gallstone prevalence in pima indian females.[1]
- The incidence/prevalence of gallbladder cancer is approximately 7.1 per 100,000 and 64.1% in North American Indian females.[2]
- The incidence/prevalence of gallbladder cancer is approximately 27.3 per 100,000 and 49.4% in Chilean Mapuche Indian females.[3]
- The incidence/prevalence of gallbladder cancer is approximately 22 per 100,000 and 21.6% in East Indian females.
Case-fatality rate/Mortality rate
- The mortality rate of gallbladder cancer is approximately 0.6%. An estimated 1,092 gallstone-related deaths for 2004 in the U.S.[4]
- cholecystectomy carries a high mortality rate at 1% and postoperative complications of >30%.[5]
- The mortality rate of gallbladder cnacers in chile is very high in the world.[6]
Age
- Clinical data shows most people with gallbladder cancer are older than 70.
- Gallbladder adenocarcinoma predominantly affects older persons with long-standing cholecystolithiasis.
Gender
- Epidemiology data shows women are about twice as likely to develop gallbladder cancer as men.
Race
- Epidemiology data demonstrates that Mexican Americans and Native Americans, particularly in the southwestern United States, are more likely to develop gallbladder cancer than the general population.
References
- ↑ Sampliner RE, Bennett PH, Comess LJ, Rose FA, Burch TA (1970). "Gallbladder disease in pima indians. Demonstration of high prevalence and early onset by cholecystography". N Engl J Med. 283 (25): 1358–64. doi:10.1056/NEJM197012172832502. PMID 5481754.
- ↑ Miquel JF, Covarrubias C, Villaroel L, Mingrone G, Greco AV, Puglielli L, Carvallo P, Marshall G, Del Pino G, Nervi F (1998). "Genetic epidemiology of cholesterol cholelithiasis among Chilean Hispanics, Amerindians, and Maoris". Gastroenterology. 115 (4): 937–46. PMID 9753497.
- ↑ Miquel JF, Covarrubias C, Villaroel L, Mingrone G, Greco AV, Puglielli L, Carvallo P, Marshall G, Del Pino G, Nervi F (1998). "Genetic epidemiology of cholesterol cholelithiasis among Chilean Hispanics, Amerindians, and Maoris". Gastroenterology. 115 (4): 937–46. PMID 9753497.
- ↑ Stinton LM, Shaffer EA (2012). "Epidemiology of gallbladder disease: cholelithiasis and cancer". Gut Liver. 6 (2): 172–87. doi:10.5009/gnl.2012.6.2.172. PMC 3343155. PMID 22570746.
- ↑ Stinton LM, Shaffer EA (2012). "Epidemiology of gallbladder disease: cholelithiasis and cancer". Gut Liver. 6 (2): 172–87. doi:10.5009/gnl.2012.6.2.172. PMC 3343155. PMID 22570746.
- ↑ Lazcano-Ponce EC, Miquel JF, Muñoz N, Herrero R, Ferrecio C, Wistuba II, Alonso de Ruiz P, Aristi Urista G, Nervi F (2001). "Epidemiology and molecular pathology of gallbladder cancer". CA Cancer J Clin. 51 (6): 349–64. PMID 11760569.