Boerhaave syndrome overview

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Feham Tariq, MD [2]

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Overview

Boerhaave syndrome or Esophageal perforation, is rupture of the esophageal wall. It is an emergency, life-threatening condition.[1] It is most often caused by excessive vomiting in eating disorders such as bulimia although it may rarely occur in extremely forceful coughing or other situations, such as obstruction by food. It can cause pneumomediastinum and/or mediastinitis (air or inflammation of the mediastinum) and sepsis.

This condition was first documented by the 18th-century physician Herman Boerhaave, after whom it is named.[2][3]

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Boerhaave syndrome overview from Other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications, and Prognosis

Natural History

Complications

Prognosis

Diagnosis

Diagnostic Criteria

History and Symptoms

Physical Examination

Laboratory Findings

Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

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Prevention

References

  1. Ishikawa Y, Tagami T, Hirashima H, Fukuda R, Moroe Y, Unemoto K (2017). "Endoscopic Treatment of Boerhaave Syndrome Using Polyglycolic Acid Sheets and Fibrin Glue: A Report of Two Cases". J Nippon Med Sch. 84 (5): 241–245. doi:10.1272/jnms.84.241. PMID 29142186.
  2. Template:WhoNamedIt
  3. H. Boerhaave. Atrocis, nec descripti prius, morbis historia: Secundum medicae artis leges conscripta. Lugduni Batavorum; Ex officine Boutesteniana. 1724.

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