Occupational lung disease epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Hadeel Maksoud M.D.[2]
Overview
Epidemiology and Demographics
Incidence and prevalence
There are no reliable figures for the incidence or prevalence of occupational lung disease.[1][2][3][4][5][6][7]
- Farmer's lung:
- The incidence for farmer's lung was 8-540 cases per 100,000 in 2012.
- Coal worker's pneumoconiosis and silicosis:
- Among coal workers worldwide:
- 30% developed coal worker's pneumonconiosis
- 2.5% developed progressive massive fibrosis
- In 30 years of exposure, 12% will develop silicosis and 20% will die from silicosis
- Asbestosis
- In 1972, it was reported that 250,000 people were at risk in the US.
Case-fatality rate/Mortality rate
- There is no reliable data for the case-fatality rate of occupational lung disease.
- Mortality rates depend on the substance inhaled, as well as the frequency, duration and dose of inhalational exposure.
- Cardiopulmonary and genetic factors of the host also contribute to mortality rate.
- Overall, there was approximately 60,3000 deaths from work-related disease in 2012.
Age
Occupational lung disease commonly affects older individuals who have been exposed longer to a particular substance.
Race
There is no racial predilection to occupational lung disease
Gender
Males are more commonly affected by occupational lung disease than females, reflecting the occupations in which exposure is present.
Region
- Occupational lung disease, particularly, coal worker's pneumoconiosis is a common disease that tends to affect coal miners in West Virginia and Kentucky, USA and South Wales, UK.
- The United Kingdom, Sweden and France have a high prevalence of farmer's lung.
- Australia, Japan, South Africa and parts of the European Union still use Asbestos as an insulation material.
- ↑ Hanak V, Golbin JM, Ryu JH (2007). "Causes and presenting features in 85 consecutive patients with hypersensitivity pneumonitis". Mayo Clin. Proc. 82 (7): 812–6. doi:10.4065/82.7.812. PMID 17605960.
- ↑ Chen S, Yuan J, Yao S, Jin Y, Chen G, Tian W, Xi J, Xu Z, Weng D, Chen J (2015). "Lipopolysaccharides may aggravate apoptosis through accumulation of autophagosomes in alveolar macrophages of human silicosis". Autophagy. 11 (12): 2346–57. doi:10.1080/15548627.2015.1109765. PMC 4835201. PMID 26553601.
- ↑ de Oliveira Abrão C, de Araújo Filho JA (2015). "Mycobacterium sherrisii Lung Infection in a Brazilian Patient with Silicosis and a History of Pulmonary Tuberculosis". Case Rep Infect Dis. 2015: 498608. doi:10.1155/2015/498608. PMC 4628689. PMID 26557395.
- ↑ Sonnenberg P, Murray J, Glynn JR, Thomas RG, Godfrey-Faussett P, Shearer S (2000). "Risk factors for pulmonary disease due to culture-positive M. tuberculosis or nontuberculous mycobacteria in South African gold miners". Eur. Respir. J. 15 (2): 291–6. PMID 10706494.
- ↑ "Advanced pneumoconiosis among working underground coal miners--Eastern Kentucky and Southwestern Virginia, 2006". MMWR Morb. Mortal. Wkly. Rep. 56 (26): 652–5. 2007. PMID 17615522.
- ↑ "Changing patterns of pneumoconiosis mortality--United States, 1968-2000". MMWR Morb. Mortal. Wkly. Rep. 53 (28): 627–32. 2004. PMID 15269698.
- ↑ Laney AS, Weissman DN (2014). "Respiratory diseases caused by coal mine dust". J. Occup. Environ. Med. 56 Suppl 10: S18–22. doi:10.1097/JOM.0000000000000260. PMC 4556416. PMID 25285970.