Diaphragmatic paralysis laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Laboratory findings consistent with the diagnosis of diaphragmatic paralysis include reduced oxygen saturation in the supine position in unilateral and bilateral diphragmatic paralysis and elevated arterial partial pressure of carbon dioxide (PaCO2) in bilateral diaphragmatic paralysis. Hpoxemia may be seen in arterial blood gas in bilateral diaphragmatic paralysis.

Laboratory Findings

  • Complete blood count is usullay done to rull out anemia as a cause of dyspnea.
  • Tyroid tests are usually done because tyroid disease is usullay associated with bilateral diaphragamtic paralysis.
  • Laboratory findings consistent with the diagnosis of diaphragmatic paralysis include:[1]
    • Reduced oxygen saturation in the supine position in unilateral and bilateral diphragmatic paralysis
    • Elevated arterial partial pressure of carbon dioxide (PaCO2) in bilateral diaphragmatic paralysis
    • Hpoxemia may be seen in arterial blood gas in bilateral diaphragmatic paralysis.
    •  P(A-a) O2 gradients may be normal if the cause of diaphragmatic paralysis is not related to underlying parenchymal lung disease.
  • Based on the causes of diaphragmatic paralysis, more laboratory tests may be needed.

References

  1. Martinez FJ, Strawderman RL, Flaherty KR, Cowan M, Orens JB, Wald J (August 1999). "Respiratory response during arm elevation in isolated diaphragm weakness". Am. J. Respir. Crit. Care Med. 160 (2): 480–6. doi:10.1164/ajrccm.160.2.9608096. PMID 10430717.

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