Respiratory acidosis natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]

Overview

Natural History^[1]^[2]

Respiration acidosis(primary hypercapnia), is the acid-base ailment that consequences from an increase in carbon dioxide in the body.
Acute respiratory acidosis happens with respiratory failure, which could result from any unexpected respiratory parenchymal, airways (eg, chronic obstructive pulmonary disease ), pleural, chest wall, neuromuscular eg, spinal cord damage, or central nervous system disorders.
Chronic respiratory acidosis can result from several procedures and is typified by way of a sustained increase in arterial partial pressure of carbon dioxide, ensuing in renal adaptation, and an extra marked increase in plasma bicarbonate.
Diffrent mechanisms of respiratory acidosis include increased carbon dioxide production, alveolar hypoventilation, abnormal breathing drive, abnormalities of the chest wall and respiratory muscles.
Despite the fact that the symptoms, signs, results of respiratory acidosis are numerous, the major effects are seen on the central nervous and cardiovascular systems which are life threating.

Prognosis depends on the disease causing the respiratory acidosis.

↑ Epstein SK, Singh N (April 2001). "Respiratory acidosis". Respir Care. 46 (4): 366–83. PMID 11262556.
↑ Johnson, Rebecca A. (2017). "A Quick Reference on Respiratory Acidosis". Veterinary Clinics of North America: Small Animal Practice. 47 (2): 185–189. doi:10.1016/j.cvsm.2016.10.012. ISSN 0195-5616.