Mesothelioma history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

Obtaining the history is the most important aspect of making a diagnosis when evaluating a patient for mesothelioma. Detailed history of the presenting symptom (onset, duration, and progression), other associated symptoms, and a thorough family and occupational history review. Other specific areas of focus include a history of any exposure to asbestos or radiation.Presenting symptoms of mesothelioma appear after 20 to 50 years of exposure to asbestos. Symptoms of mesothelioma include chest pain nonpleuritic in nature, shortness of breath, cough, fatigue, palpitation, hemoptysis, fever and weight loss.

History

  • Obtaining the history is the most important aspect of making a diagnosis when evaluating a patient for mesothelioma.[1][2]
  • A detailed history of the presenting symptom (onset, duration, and progression), other associated symptoms, and a thorough family and occupational history review. Other specific areas of focus include a history of any exposure to asbestos or radiation.

Symptoms

Mesothelioma that affects the pleura can cause:

Mesothelioma that affects the peritoneum can cause:

Mesothelioma that affects the pericardium can cause:

References

  1. Risk factors for mesothelioma. Canadian cancer society 2016. http://www.cancer.ca/en/cancer-information/cancer-type/mesothelioma/risks/?region=on. Accessed on February 16, 2016
  2. Bianco A, Valente T, De Rimini ML, Sica G, Fiorelli A (January 2018). "Clinical diagnosis of malignant pleural mesothelioma". J Thorac Dis. 10 (Suppl 2): S253–S261. doi:10.21037/jtd.2017.10.09. PMC 5830561. PMID 29507793.
  3. Yang H, Testa JR, Carbone M (June 2008). "Mesothelioma epidemiology, carcinogenesis, and pathogenesis". Curr Treat Options Oncol. 9 (2–3): 147–57. doi:10.1007/s11864-008-0067-z. PMC 2717086. PMID 18709470.
  4. Bianco A, Valente T, De Rimini ML, Sica G, Fiorelli A (January 2018). "Clinical diagnosis of malignant pleural mesothelioma". J Thorac Dis. 10 (Suppl 2): S253–S261. doi:10.21037/jtd.2017.10.09. PMC 5830561. PMID 29507793.


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