Granulomatosis with polyangiitis risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Ali Poyan Mehr, M.D. [2]Associate Editor(s)-in-Chief: Amandeep Singh M.D.[3]

Overview

Common risk factors in the development of [disease name] may be occupational, environmental, genetic, and viral.

Common risk factors in the development of granulomatosis with polyangitis(GPA)] may be occupational, environmental, genetic
Common risk factors in the development of GPA include:
- Age= 40-65 years
- Genetic= HLA DPB1^[1]
  - Variant HLA-DPB1*0401 in those associated with ANCA ^[2]^[3]
- [Risk factor 3]

Less common risk factors in the development of [disease name] include:
- [Risk factor 1]
- [Risk factor 2]
- [Risk factor 3]

↑ Wieczorek S, Holle JU, Epplen JT (January 2010). "Recent progress in the genetics of Wegener's granulomatosis and Churg-Strauss syndrome". Curr Opin Rheumatol. 22 (1): 8–14. doi:10.1097/BOR.0b013e3283331151. PMID 19864953.
↑ https://ghr.nlm.nih.gov/condition/granulomatosis-with-polyangiitis#sourcesforpage
↑ Jagiello P, Gencik M, Arning L, Wieczorek S, Kunstmann E, Csernok E, Gross WL, Epplen JT (April 2004). "New genomic region for Wegener's granulomatosis as revealed by an extended association screen with 202 apoptosis-related genes". Hum. Genet. 114 (5): 468–77. doi:10.1007/s00439-004-1092-z. PMID 14968360.