Autoimmune hemolytic anemia laboratory findings
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Assosciate Editor(s)-In-Chief: Prashanth Saddala M.B.B.S
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Overview
Laboratory Findings
- Tests include:
- Direct Coombs' test: This is also known at the direct antiglobulin test. This test assesses for the presence of antibodies attached to a patient's red blood cells. The test is performed by collecting peripheral blood containing red blood cells, which theoretically harbor antibodies in their surface, then adding in a Coombs' reagent and assessing for agglutination. Of note, the Coombs' test can be negative in 3-10% of patients.[1]
- Hemoglobin in the urine
- Indirect Coombs' test
- Red blood cell count and serum hemoglobin - anemia
- Reticulocyte count
- Serum bilirubin levels
- Serum haptoglobin
References
- ↑ Berentsen S, Sundic T (2015). "Red blood cell destruction in autoimmune hemolytic anemia: role of complement and potential new targets for therapy". Biomed Res Int. 2015: 363278. doi:10.1155/2015/363278. PMC 4326213. PMID 25705656.