Takayasu's arteritis history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Farnaz Khalighinejad, MD [2]
Overview
History
Takayasu's arteritis can be divided into two phases:[1][2]
- Pre-pulseless phase
- Present with non-specific constitutional symptoms of vasculitis, which may include any of the following
- Subsequent pulseless phase
- With progression of the disease and involvement of the branches of aorta, specific symptoms secondary to narrowing/occlusion of the branches of aorta become evident.
- Subclavian artery:
- Carotid and vertebral arteries:
- Coronary arteries:
- Chest pain
- Angina which may progress to myocardial infarction
- Ascending aorta:
- With progression of the disease and involvement of the branches of aorta, specific symptoms secondary to narrowing/occlusion of the branches of aorta become evident.
Common Symptoms
Common symptoms of Takayasu's arteritis include:
- Bruit
- The most common location being the carotid artery
- Blood pressure difference of extremities
- Claudication
- Hypertension
- Visual disturbance
Less Common Symptoms
Less common symptoms of Takayasu's arteritis include:
- Fever
- Weight loss
- Carotodynia or vessel tenderness
- Raynaud syndrome
- Stroke
- Transient ischemic attacks
- Seizures
- Erythema nodosum
- Ulcerated subacute nodular lesions
- Pyoderma gangrenosum
- Angina
- Gastrointestinal symptoms
References
- ↑ Kerr GS, Hallahan CW, Giordano J, Leavitt RY, Fauci AS, Rottem M, Hoffman GS (June 1994). "Takayasu arteritis". Ann. Intern. Med. 120 (11): 919–29. PMID 7909656.
- ↑ Mason JC (July 2010). "Takayasu arteritis--advances in diagnosis and management". Nat Rev Rheumatol. 6 (7): 406–15. doi:10.1038/nrrheum.2010.82. PMID 20596053.